Matthew E Brown
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Matthew Brown

Discovery Spotlight

Brown Lab

Matthew E Brown, PhD

 

 

Assistant Professor, Director, UW Humanized Mouse Core Service

 

Department of Surgery – Transplantation

 

The Brown Lab focuses on exploring the nexus of pluripotent stem cell biology and immunology. We are currently investigating the mechanisms underpinning the immune response to autologous and allogeneic pluripotent stem cell (PSC)-derived cell therapies. Using transplantation immunology and genomics-based strategies, in conjunction with humanized mouse models, our goals are to 1) improve traditional organ transplantation outcomes, 2) gain new insights into PSC biology and immunology, and 3) enable curative regenerative medicine therapies.

 

Key Publications:
NeoThy Humanized Mouse Model
Human T Cell Reprogramming

 

Publications:
www.ncbi.nlm.nih.gov/myncbi/matthew.brown.8/bibliography/public