Aaron A. Hoskins
1610
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Discovery Spotlight

Aaron A. Hoskins, PhD

 

Wasson Professor
Department of Biochemistry

 

Biomolecular Folding & Interactions; Chemical Biology & Enzymology; Gene Expression & RNA Biology; Quantitative Biology

 

Dr. Hoskins is a biochemist and biophysicist studying the molecular mechanisms behind gene expression and how these steps can go wrong in diseases like blood cancers. Our goals are to discover new, fundamental biological mechanisms that control gene expression in all eukaryotes ranging from Baker’s yeast to humans. Currently, a major research focus for the Hoskins Lab is to understand how the pre-mRNA splicing machinery can be targeted by anticancer therapeutics and uncovering the mechanisms of action for these drugs. Our work uses a variety of methods including single molecule biophysics, in vitro biochemistry, and experiments in a variety of organisms including fungal and human cells. 

 

Publications:
https://hoskins.biochem.wisc.edu/pubs.php