Department of Medical Microbiology and Immunology
Sexual dimorphism in immune-associated diseases
Hematologic malignancies occur more commonly in men than in women, and this male bias in cancer susceptibility can be generalized to other cancers. In contrast, autoimmune diseases occur predominately in women. Our lab is interested in understanding the molecular basis underlying the observed dichotomy in disease susceptibility. Our ultimate goal is to identify new risk factors for immunological diseases, and guide personalized treatment to address the sex-specific effects of drugs.